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Power PDF: Receiving the error message "This file cannot be found" when opening a PDF from imanage Desksite

Question:  

Receiving the error message "This file cannot be found" when opening a PDF from imanage Desksite Open PDF from iManage using the iManage connector in PowerPDF.  

Answer:  

The customer had to adjust the setting on the Work server with the Local Application for Nuance.  It was set to non-integrated and should have been set to Com-Integrated.